Foot-and-Mouth disease virus serotype Identification


The Foot-and-Mouth disease virus serotype Identification  dtec-RT-qPCR-Panel-7 comprises a series of specific targeted reagents designed for Serotypes of Foot-and-Mouth disease virus A, C, O, Asia 1, SAT 1, SAT 2 and SAT3 detection by using qPCR. Foot-and-Mouth disease or Hoof-and-Mouth disease (Aphthae epizooticae) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild animals. Foot-and-Mouth disease is highly infectious and can be spread by infected animals through aerosols, through contact with contaminated farming equipment, vehicles, clothing or feed, and by domestic and wild predators. Foot-and-Mouth disease is caused by a picornavirus, a non-enveloped, positive-stranded RNA virus with an icosahedral capsid and genetically highly variable. Of the seven described serotypes of this virus, A, C, O, Asia 1 and SAT3 appear to be distinct lineages; SAT 1 and SAT 2 are unresolved clades. Type O is the most prevalent of the seven serotypes and occurs in many parts of the world. Eight distinct genetic lineages are identified, which fall into geographically distinct regions: Europe-South America, Middle East-South Asia, South-East Asia, Cathay (China and east Tartary), West Africa, East Africa, Indonesia-1 and Indonesia-2. Type A viruses have always been considered to be antigenically the most diverse of the European serotypes, can be grouped into three major geographically restricted genotypes: Europe-South America, Asia and Africa. Type C appears to have become confined to the Indian sub-continent. Type Asia 1 normally only occurs in southern Asia and have been considered less diverse than other serotypes. Type SAT-1 is of particular importance due to its extensive distribution throughout sub-Saharan Africa and previous incursion into North Africa and the Middle East. Type SAT-2 occurs throughout sub-Saharan Africa and has made recent incursions into the Middle East from north-east Africa. Type SAT-3 has the most restricted distribution mainly located on Zimbabwe.


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GPS™ primers and probes are sold for research use only

All GPS™ Kits are available in F100 and MONODOSE Format

GPS™ reagents are compatible with all qPCR devices

Manufacturer: genetic PCR solutions™