Actinobacillus pleuropneumoniae omlA V

Description

The ActPle-omlAV dtec-qPCR comprises a series of specific targeted reagents designed for Actinobacillus pleuropneumoniae omlA V detection by using qPCR. Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae) is a non-motile, Gram-negative, encapsulated coccobacillus from the family Pasteurellaceae. It causes porcine pleuropneumonia, a highly contagious respiratory disease in young pigs, particularly under 6 months old. Symptoms include respiratory distress, bloodstained discharge, fever, cyanosis, anorexia, and spontaneous abortion in sows. Mortality rates can reach 20-80% in fattening pigs, with high morbidity. Survivors often become carriers, further spreading the infection. There are two biotypes and at least 15 serotypes, all of which can cause disease.  The variation in virulence between serotypes is attributed to the differential expression of virulence factors, including the omlA gene, which encodes a key outer membrane lipoprotein crucial for pathogenicity. The omlA V variant in A. pleuropneumoniae is linked to strains of low virulence, though it can still cause symptoms. Detecting this variant is crucial for effective disease control and prevention measures.

Kit Content and Prices

F100

MONODOSE

List of Available Kits

GPS™ primers and probes are sold for research use only

All GPS™ Kits are available in F100 and MONODOSE Format

GPS™ reagents are compatible with all qPCR devices