The CloDif dtec-qPCR comprises a series of species-specific targeted reagents designed for Clostridium difficile detection by using qPCR. Clostridium difficile is a Gram-positive, anaerobic, motile, ubiquitous and spore-forming bacteria from the family Clostridiaceae. Sometimes antibiotic therapy for various infections has the adverse effect of disrupting the normal balance of the gut flora, in which case C. difficile may opportunistically dominate, causing Clostridium difficile colitis. Pathogenic C. difficile strains produce multiple toxins. The most characterized are enterotoxin (Clostridium difficile toxin A) and cytotoxin (Clostridium difficile toxin B), both of which may produce diarrhea and inflammation in infected patients. Most cases of Clostridium difficile colitis are nosocomial infection.
Kit Content and Prices
GPS™ primers and probes are sold for research use only
All GPS™ Kits are available in F100 and MONODOSE Format
GPS™ reagents are compatible with all qPCR devices