The CloPer-Epsilon dtec-qPCR comprises a series of specific targeted reagents designed for Epsilon toxin of Clostridium perfringens detection by using qPCR. Clostridium perfringens (formerly known as C. welchii, or Bacillus welchii) is a spore-forming Gram-positive bacterium that is found in many environmental sources as well as in the intestines of humans and animals. C. perfringens is responsible of food poisoning, gastrointestinal disease, gas gangrene and related necrotic conditions in humans and other mammals. This bacterium produces 4 major toxins (named Alpha, Beta, Epsilon and Iota). Epsilon toxins is produced by type B and type D strains of C. perfringens and is most commonly isolated from animals, particularly sheep, goats, and cattle, but rarely from humans. Epsilon toxin creates pores in tissues, resulting in leaked potassium ions and fluid leakage, which leads to greater complications, giving way to the symptoms associated with C. perfringens infection. Two common diseases seen in animals as a result from type B and D strains of C. perfringens are lamb dysentery and pulpy kidney disease.

Kit Content and Prices

F100

MONODOSE