The FMDV-A MONODOSE RT-qPCR comprises a series of specific targeted reagents designed for Foot-and-mouth disease virus type A detection by using qPCR. Foot-and-mouth disease virus is a non-enveloped, positive-sense single-stranded RNA virus belonging to the family Picornaviridae and the genus Aphthovirus. It primarily affects cloven-hoofed animals such as cattle, pigs, sheep, goats, and various wild ungulates. It causes foot-and-mouth disease, also known as hoof-and-mouth disease or Aphthae epizooticae, which is highly contagious and sometimes fatal. Infected animals exhibit clinical signs including fever, followed by the development of vesicles and erosions in the mouth, on the feet, and on the mammary glands, often resulting in lameness, reduced milk production, and significant economic losses. Transmission occurs through direct contact with infected animals, aerosols, fomites, and contaminated animal products. Of the seven described serotypes of this virus, A, C, O, ASIA1 and SAT3 appear to be distinct lineages; SAT1 and SAT2 are unresolved clades. Type A is one of the most antigenically diverse serotypes, exhibiting a wide geographic distribution and being categorised into three major, geographically distinct genotypes: Europe-South America, Asia, and Africa. Due to the elevated mutation rate of the species, the emergence of new strains may affect specificity. Some novel clones may not be detected, or may yield weaker signal.

Kit Content and Prices

F100

MONODOSE