The SBV RT-qPCR comprises a series of species-specific targeted reagents designed for detection of Schmallenberg virus by using qPCR. Schmallenberg virus (SBV) is the informal name given to a recently isolate dorthobunya virus, which has not been given a formal name as of January 2013, initially reported in November 2011 to cause congenital malformations and stillbirths in cattle, sheep, goats, and possibly alpaca. It appears to be transmitted bymidges (Culicoides spp.) which are likely to have been most active in causing the infection in the northern hemisphere summer and autumn of 2011. After Germany, it has also been detected in most countries of Europe. Russia, Ukraine, Kazakhstan, Egyptand,Mexico have all suspended imports of live cattle and sheep, along with embryos and semen from affected countries.

Product Supporting Literature

Boshra, H., Lorenzo, G., Charro, D., Moreno, S., Guerra, G.S., Sanchez, I., Garrido, J.M., Geijo, M., Brun, A., Abrescia, N.G.A., 2020. A novel Schmallenberg virus subunit vaccine candidate protects IFNAR-/- mice against virulent SBV challenge. Sci. Rep. 10, 18725.

Boshra, H.Y., Charro, D., Lorenzo, G., Sánchez, I., Lazaro, B., Brun, A., Abrescia, N.G.A., 2017. DNA vaccination regimes against Schmallenberg virus infection in IFNAR−/− mice suggest two targets for immunization. Antiviral Res. 141, 107–115.

Guerra, G.S., Barriales, D., Lorenzo, G., Moreno, S., Anguita, J., Brun, A., Abrescia, N.G.A., 2023. Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR-/- mice. Vaccine 41, 3275–3284.

Kit Content and Prices

F100

MONODOSE