The Tick-Borne Hemoparasites dtec-qPCR-Panel-4 comprises a series of specific targeted reagents designed for Ehrlichia spp., Anaplasma phagocytophylum, Borrelia burgdorferi and Babesia spp. detection by using qPCR. Tick-borne pathogens are responsible for several serious diseases in both humans and animals. Ehrlichia spp. species are small, Gram-negative, obligate intracellular bacteria that cause infection (Ehrlichiosis) in humans. These zoonotic pathogens primarily reside in animal reservoirs such as rodents, deer, roe deer, foxes, cattle, sheep, goats, horses, and dogs. In humans, the infection manifests as a nonspecific flu-like illness. Anaplasma phagocytophilum is a species  of rickettsial bacteria in the Ehrlichiaceae family, causing the disease anaplasmosis by living in host blood cells and requiring ticks for maturation. Infection leads to hemolytic anemia due to red blood cell damage in dogs, cats, horses and humans. Borrelia burgdorferi is a Gram-negative bacterium of the Borrelia genus.  It is the causative agent of Lyme disease, which is transmitted form bacteria to humans. Sympthoms include erythema chronicum migrans, myocarditis, cardiomyopathy, arrythmia, arthritis, arthralgia, meningitis, neuropathies, and facial nerve palsy.  Babesia (also called nuttallia) is a genus of protozoan Apicomplexan piroplasms causing babesiosis, a hemolytic disease. With over 100 identified species, only a few are pathogenic to humans. Historically, babesiosis has been a significant illness for wild and domesticated animals, particularly cattle.

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F100

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