The VR-vanB dtec-qPCR comprises a series of specific targeted reagents designed for Vancomicin resistance vanB detection by using qPCR. Vancomycin is a glycopeptide used for its bactericidal effect to treat infections caused by Gram-positive bacteria.  It binds to the bacterial cell envelope rather than to a protein target, as is the case for other antibiotics. Vancomycin’s therapeutic efficacy is threatened by two types of complex resistance mechanisms, each involving a multi-enzyme route, that are becoming extensively more common in pathogenic species. The vanB resistance gene cluster resides on the transposon Tn1547, more commonly found in bacterial chromosomes, but it can also be found on plasmids. Only vancomycin, but not teicoplanin, induces vanB resistance.

Kit Content and Prices

F100

MONODOSE