Actinobacillus pleuropneumoniae Apx IV toxin


The ActPle-ApxIV dtec-qPCR comprises a series of specific targeted reagents designed for Actinobacillus pleuropneumoniae Apx IV toxin detection by using qPCR. Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae), is a non-motile, Gram-negative, encapsulated coccobacillus bacterium of the Pasteurellaceae family. It is a respiratory pathogen found in pigs responsible for up to 20 % of all bacterial pneumonia cases in swine. Infection leads to the development of porcine pleuropneumonia, a highly contagious respiratory disease affecting pigs under 6 months. Symptoms include respiratory distress, bloodstained discharge from the mouth, fever, anorexia, mild diarrhoea, cyanosis, lethargy, and spontaneous abortion in sows. Mortality rates can reach 20-80 % in fattening pigs, having a profound economic impact. Pigs that do survive the disease remain as carriers and spread the bacterium. Several virulence factors account for the remarkable pathogenicity of this organism, among which is the production and release of the ApxIV toxin, expressed in all 15 serotypes identified so far.

Kit Content and Prices



List of Available Kits

GPS™ primers and probes are sold for research use only

All GPS™ Kits are available in F100 and MONODOSE Format

GPS™ reagents are compatible with all qPCR devices