The CAEV dtec-RT-qPCR comprises a series of specific targeted reagents designed for Caprine arthritis encephalitis virus detection by using qPCR. Caprine arthritis encephalitis virus is an enveloped, single-stranded RNA lentivirus belonging to the family Retroviridae. As part of their life cycle, once the viral RNA enters to the cytoplasm DNA is produced by using its own reverse transcriptase. The new DNA is then incorporated into the host cell genome by an integrase enzyme, at this point the retroviral DNA is referred to as a provirus. The virus adversely affects the immune system of its host, causing a disease known as caprine arthritis encephalitis, which is widely disseminated in goat herds on different continents. Common symptoms include arthritis, pneumonia, indurative mastitis, and encephalitis. However, many goats will not show any symptoms. By far, the most important source of infection, is the milk of positive animals. In fact, if the kids are fed with communal milk from the herd, all the kids can be infected by just a single positive goat. As an effective vaccination does not exist, eradication programs are essential as well as fast detection of infected animals.
Kit Content and Prices
GPS™ primers and probes are sold for research use only
All GPS™ Kits are available in F100 and MONODOSE Format
GPS™ reagents are compatible with all qPCR devices