The FraTul-pilA epPCR comprises a series of specific targeted reagents designed for Francisella tularensis pilA virulence detection by using epPCR. Francisella tularensis is a non-motile, non-spore forming, Gram-negative, highly contagious bacteria that causes tularemia (or “rabbit fever”) that is contagious to humans. Tularemia can lead to different clinical signs as ulceroglandular, glandular or typhoidal. F. tularensis is a highly contagious bacteria that can be spread from animals to humans, through vectors such as mosquitos and fleas, or from being breathed in from the air. The bacteria infects humans through skin, mucous membranes, lungs, and the gastrointestinal tract. There are four known subspecies of F. tularensis with different degrees of virulence and geographical distribution. Some published studies have shown that one pilin gene, pilA, contribute to virulence in highly virulent strains. Due to its low infectious dose, ease of spread by aerosol, and high virulence, F. tularensis is classified as a potential agent of bioterrorism.
Kit Content and Prices
GPS™ primers and probes are sold for research use only
All GPS™ Kits are available in F100 and MONODOSE Format
GPS™ reagents are compatible with all qPCR devices