Vancomicin resistance vanA
Description
The VR-vanA dtec-qPCR comprises a series of specific targeted reagents designed for Vancomicin resistance vanA detection by using qPCR. Vancomycin is a glycopeptide used for its bactericidal effect to treat infections caused by Gram-positive bacteria. It binds to the bacterial cell envelope rather than to a protein target, as is the case for other antibiotics. Vancomycin’s therapeutic efficacy is threatened by two types of complex resistance mechanisms, each involving a multi-enzyme route, that are becoming extensively more common in pathogenic species. The vanA gene cluster, found on transposon Tn1546, controls vancomycin resistance, which can be induced after treatment with either vancomycin or teicoplanin.
Kit Content and Prices
GPS™ primers and probes are sold for research use only
All GPS™ Kits are available in F100 and MONODOSE Format
GPS™ reagents are compatible with all qPCR devices